Gene

vps36

ID
ZDB-GENE-030131-7753
Name
vacuolar protein sorting 36 homolog
Symbol
vps36 Nomenclature History
Previous Names
  • fj33d07
  • wu:fj33d07
  • zgc:55965
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable ubiquitin binding activity. Predicted to be involved in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to act upstream of or within endosome transport via multivesicular body sorting pathway and protein transport. Predicted to be located in endosome. Predicted to be part of ESCRT II complex. Predicted to be active in late endosome membrane. Orthologous to human VPS36 (vacuolar protein sorting 36 homolog).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Gulluni et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la010265TgTransgenic insertionUnknownUnknownDNA
la017473TgTransgenic insertionUnknownUnknownDNA
la027156TgTransgenic insertionUnknownUnknownDNA
sa41659Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-vps36N/AGulluni et al., 2021
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Human Disease
Associated With vps36 Human Ortholog
No data available
Associated With vps36 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR021648 Vacuolar protein sorting protein 36, GLUE domain
Family IPR037855 Vacuolar protein sorting protein 36
Family IPR040608 Snf8/Vps36 family
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length PH-like domain superfamily Snf8/Vps36 family Vacuolar protein sorting protein 36 Vacuolar protein sorting protein 36, GLUE domain Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q7ZVK4 InterPro 382
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 10
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA vps36-201 (1) Ensembl 1,904 nt
mRNA vps36-202 (1) Ensembl 610 nt
mRNA vps36-203 (1) Ensembl 658 nt
mRNA vps36-206 (1) Ensembl 4,791 nt
ncRNA vps36-002 (1) Ensembl 908 nt
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Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-VPS36 polyclonal Rabbit
  • IHC
  • WB
Sigma-Aldrich
Abcam plc
1
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Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-287A12ZFIN Curated Data
EncodesESTeu191
    Thisse et al., 2005
    EncodesESTfj33d07
    EncodescDNAMGC:55965ZFIN Curated Data
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanVPS3613
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    MouseVps368
    Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Citations
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