Gene
gngt1
- ID
- ZDB-GENE-030131-7596
- Name
- guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
- Symbol
- gngt1 Nomenclature History
- Previous Names
-
- gng1
- wu:fk53d06
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Is expressed in brain; testis; and visual system. Orthologous to several human genes including GNGT1 (G protein subunit gamma transducin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 28 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73318 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | G-protein gamma-like domain | G-protein gamma-like domain superfamily | G-protein, gamma subunit |
|---|---|---|---|---|---|
| UniProtKB:Q6PBN9 | InterPro | 73 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-120E1 | ZFIN Curated Data | |
| Contained in | BAC | CH211-262K23 | ZFIN Curated Data | |
| Encodes | EST | fk53d06 | ||
| Encodes | cDNA | MGC:73318 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_199967 (1) | 704 nt | ||
| Genomic | GenBank:BX537314 (1) | 168538 nt | ||
| Polypeptide | UniProtKB:Q6PBN9 (1) | 73 aa |
- Volkov, L.I., Ogawa, Y., Somjee, R., Vedder, H.E., Powell, H.E., Poria, D., Meiselman, S., Kefalov, V.J., Corbo, J.C. (2024) Samd7 represses short-wavelength cone genes to preserve long-wavelength cone and rod photoreceptor identity. Proceedings of the National Academy of Sciences of the United States of America. 121:e2402121121e2402121121
- Drepanos, L., Gans, I.M., Grendler, J., Guitar, S., Fuqua, J.H., Maki, N.J., Tilden, A.R., Graber, J.H., Coffman, J.A. (2023) Loss of Krüppel-like factor 9 deregulates both physiological gene expression and development. Scientific Reports. 13:1223912239
- Ogawa, Y., Corbo, J.C. (2021) Partitioning of gene expression among zebrafish photoreceptor subtypes. Scientific Reports. 11:17340
- Henson, H.E., Taylor, M.R. (2020) A sart1 Zebrafish Mutant Results in Developmental Defects in the Central Nervous System. Cells. 9(11):
- Li, X., Xiong, D., Ju, Z., Xiong, Y., Ding, G., Liao, G. (2020) Phenotypic and transcriptomic consequences in zebrafish early-life stages following exposure to crude oil and chemical dispersant at sublethal concentrations. The Science of the total environment. 763:143053
- Shi, W.J., Huang, G.Y., Jiang, Y.X., Ma, D.D., Chen, H.X., Huang, M.Z., Hou, L.P., Xie, L., Ying, G.G. (2020) Medroxyprogesterone acetate affects eye growth and the transcription of associated genes in zebrafish. Ecotoxicology and environmental safety. 193:110371
- von der Heyde, B., Emmanouilidou, A., Mazzaferro, E., Vicenzi, S., Höijer, I., Klingström, T., Jumaa, S., Dethlefsen, O., Snieder, H., de Geus, E., Ameur, A., Ingelsson, E., Allalou, A., Brooke, H.L., den Hoed, M. (2020) Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach. Scientific Reports. 10:11831
- Shi, W.J., Jiang, Y.X., Ma, D.D., Huang, G.Y., Xie, L., Chen, H.X., Huang, M.Z., Ying, G.G. (2019) Dydrogesterone affects the transcription of genes in visual cycle and circadian rhythm network in the eye of zebrafish. Ecotoxicology and environmental safety. 183:109556
- Schredelseker, T., Driever, W. (2018) Bsx controls pineal complex development. Development (Cambridge, England). 145(13):
- Sun, C., Galicia, C., Stenkamp, D.L. (2018) Transcripts within rod photoreceptors of the Zebrafish retina. BMC Genomics. 19:127
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