Gene
tubb2b
- ID
- ZDB-GENE-030131-722
- Name
- tubulin, beta 2b
- Symbol
- tubb2b Nomenclature History
- Previous Names
-
- fb40f09
- wu:fb40f09 (1)
- zgc:123194
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within microtubule-based process. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Human ortholog(s) of this gene implicated in Leber congenital amaurosis with early-onset deafness and complex cortical dysplasia with other brain malformations 7. Orthologous to several human genes including TUBB4B (tubulin beta 4B class IVb).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| complex cortical dysplasia with other brain malformations 7 | Alliance | Cortical dysplasia, complex, with other brain malformations 7 | 610031 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Length |
|---|---|
|
UniProtKB:A0A0R4IPH2
|
445 |
|
UniProtKB:A0A8M1N7Z8
|
472 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
tubb2b-201
(1)
|
1568 nt |
Interactions and Pathways
No data available
Plasmids
No data available