Gene
setdb2
- ID
- ZDB-GENE-030131-7093
- Name
- SET domain bifurcated histone lysine methyltransferase 2
- Symbol
- setdb2 Nomenclature History
- Previous Names
-
- wu:fk80d09
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Description
- Exhibits histone methyltransferase activity (H3-K9 specific). Involved in several processes, including embryonic morphogenesis; histone H3-K9 methylation; and left/right axis specification. Predicted to localize to nucleus. Orthologous to human SETDB2 (SET domain bifurcated histone lysine methyltransferase 2).
- Genome Resources
-
- Alliance (1)
- Gene:335153 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) Single Cell Expression Atlas (1) Daniocell (1)
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | DNA-binding domain superfamily | Histone-lysine N-methyltransferase SETDB | Methyl-CpG DNA binding | Pre-SET domain | SET domain | SET domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q06ZW3
|
551 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-setdb2 | polyclonal | Rabbit |
|
1 |
Plasmids
No data available
- Comparative Orthology
- Alliance