Gene
ppp1cbl
- ID
- ZDB-GENE-030131-6529
- Name
- protein phosphatase 1, catalytic subunit, beta isoform, like
- Symbol
- ppp1cbl Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Exhibits protein heterodimerization activity. Involved in convergent extension involved in axis elongation. Predicted to localize to cytoplasm and nucleus. Orthologous to human PPP1CB (protein phosphatase 1 catalytic subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7142005 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Jayashankar et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Noonan syndrome-like disorder with loose anagen hair 2 | Alliance | Noonan syndrome-like disorder with loose anagen hair 2 | 617506 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004843 | Calcineurin-like phosphoesterase domain, ApaH type |
| Domain | IPR006186 | Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase |
| Domain | IPR031675 | Serine-threonine protein phosphatase, N-terminal |
| Family | IPR050341 | Serine/threonine-protein phosphatase PP1 catalytic subunit |
| Homologous_superfamily | IPR029052 | Metallo-dependent phosphatase-like |
Domain Details Per Protein
| Protein | Length | Calcineurin-like phosphoesterase domain, ApaH type | Metallo-dependent phosphatase-like | Serine-threonine protein phosphatase, N-terminal | Serine/threonine-protein phosphatase PP1 catalytic subunit | Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7T313
|
281 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppp1cbl-201
(1)
|
Ensembl | 693 nt |
Interactions and Pathways
No data available
Plasmids
No data available