FIGURE
Fig. 4
- ID
- ZDB-FIG-091216-10
- Publication
- Feitsma et al., 2008 - Alkylation damage causes MMR-dependent chromosomal instability in vertebrate embryos
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Fig. 4
MMR-dependent ENU-induced chromosomal instability arises during replication. (A) Induction of random DSBs during all phases of the cell cycle by IR does not result in surivival differences in between msh6-/- and wild-type embryos. (B) ENU sensitivity of wild-type and ku70 mutant. (C) IR sensitivity of wild type, tp53 mutant (control) and homozygous ku70 mutant. Asterisks indicate significant differences. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | 30%-epiboly |
Phenotype Detail
Acknowledgments
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Open Access article
Full text @ Nucleic Acids Res.