ZFIN is now using GRCz12tu for Genomic Data
        
        
        Gene
tnfaip1
- ID
- ZDB-GENE-030131-5610
- Name
- tumor necrosis factor, alpha-induced protein 1 (endothelial)
- Symbol
- tnfaip1 Nomenclature History
- Previous Names
- 
    
        
    
    
        
        - wu:fi06b02
- zgc:55302
 
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in negative regulation of Rho protein signal transduction; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to act upstream of or within protein homooligomerization. Predicted to be located in endosome and nucleus. Predicted to be part of Cul3-RING ubiquitin ligase complex. Orthologous to human TNFAIP1 (TNF alpha induced protein 1).
- Genome Resources
- Note
- None
- Comparative Information
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- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
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        - MGC:55302 (1 image)
 
                
                    
                        Wild Type Expression Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    - All Phenotype Data
- 4 figures from Huang et al., 2023
- Cross-Species Comparison
- Alliance
                
                    
                        Phenotype Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Mutations
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Human Disease
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Domain, Family, and Site Summary
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    
    
    
            
        
    
    
    
                
                    
                        Domain Details Per Protein
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Protein | Additional Resources | Length | BTB/POZ domain | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1-3 | Potassium channel tetramerisation-type BTB domain | SKP1/BTB/POZ domain superfamily | 
|---|---|---|---|---|---|---|
| UniProtKB:F1R5K5 | InterPro | 320 | ||||
| UniProtKB:Q7ZYX6 | InterPro | 320 | 
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis | 
|---|---|---|---|---|---|
| aberrant processed transcript | tnfaip1-202
                             (1) | Ensembl | 827 nt | ||
| mRNA | tnfaip1-201
                             (1) | Ensembl | 1,928 nt | ||
| mRNA | tnfaip1-203
                             (1) | Ensembl | 765 nt | ||
| mRNA | tnfaip1-204
                             (1) | Ensembl | 873 nt | ||
| mRNA | tnfaip1-205
                             (1) | Ensembl | 994 nt | 
                
                    
                        Interactions and Pathways
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    
                
                    
                        Plasmids
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    - Genome Browsers
