Gene
nanog
- ID
- ZDB-GENE-030131-5486
- Name
- nanog homeobox
- Symbol
- nanog Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Enables several functions, including DNA-binding transcription factor activity; chromatin binding activity; and identical protein binding activity. Involved in nucleosome organization. Acts upstream of or within with a positive effect on yolk syncytial layer development. Acts upstream of or within several processes, including cytoskeleton organization; negative regulation of beta-catenin-TCF complex assembly; and negative regulation of canonical Wnt signaling pathway. Predicted to be located in nucleus. Is expressed in several structures, including blastoderm; blastodisc; neuronal stem cell; reproductive system; and unfertilized egg. Orthologous to several human genes including NANOG (Nanog homeobox) and NANOGP1 (Nanog homeobox pseudogene 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 27 figures from 9 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeobox NK-like transcription regulators | Homeodomain |
|---|---|---|---|---|---|---|
| UniProtKB:A5JNG8 | InterPro | 384 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available