Gene
rhot1a
- ID
- ZDB-GENE-030131-5354
- Name
- ras homolog family member T1a
- Symbol
- rhot1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in cellular homeostasis; mitochondrial outer membrane permeabilization; and mitochondrion transport along microtubule. Predicted to act upstream of or within small GTPase-mediated signal transduction. Located in mitochondrion. Is expressed in fin bud; head; muscle; and somite. Orthologous to human RHOT1 (ras homolog family member T1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55581 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Hollister et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Domain | IPR002048 | EF-hand domain |
| Domain | IPR005225 | Small GTP-binding domain |
| Domain | IPR013566 | Mitochondrial Rho GTPase 1/3, EF hand associated, type-1 |
| Domain | IPR013567 | EF hand associated, type-2 |
| Domain | IPR020860 | MIRO domain |
| Family | IPR001806 | Small GTPase |
| Family | IPR021181 | Mitochondrial Rho GTPase |
| Family | IPR052266 | Mitochondrial Rho GTPase/EF-hand domain-containing protein |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | EF-Hand 1, calcium-binding site | EF hand associated, type-2 | EF-hand domain | EF-hand domain pair | MIRO domain | Mitochondrial Rho GTPase | Mitochondrial Rho GTPase 1/3, EF hand associated, type-1 | Mitochondrial Rho GTPase/EF-hand domain-containing protein | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B0X9 | InterPro | 643 | |||||||||||
| UniProtKB:Q6NVC5 | InterPro | 619 | |||||||||||
| UniProtKB:A0A8M3AQV6 | InterPro | 660 | |||||||||||
| UniProtKB:A0A8M3B899 | InterPro | 709 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rhot1a-201
(1)
|
Ensembl | 780 nt | ||
| mRNA |
rhot1a-203
(1)
|
Ensembl | 3,064 nt | ||
| mRNA |
rhot1a-205
(1)
|
Ensembl | 2,436 nt | ||
| ncRNA |
rhot1a-003
(1)
|
Ensembl | 738 nt | ||
| ncRNA |
rhot1a-004
(1)
|
Ensembl | 505 nt |
Interactions and Pathways
No data available
Plasmids
No data available