Gene

hhip

ID
ZDB-GENE-030131-4827
Name
hedgehog interacting protein
Symbol
hhip Nomenclature History
Previous Names
  • Hip (1)
  • fd99f01
  • uki
  • ukkie
  • wu:fc52e12
  • wu:fd99f01
  • zgc:153478
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have catalytic activity. Involved in fin development; negative regulation of muscle organ development; and negative regulation of smoothened signaling pathway. Localizes to intrinsic component of plasma membrane. Is expressed in several structures, including axis; mesoderm; muscle cell; nervous system; and pharyngeal arch. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Orthologous to human HHIP (hedgehog interacting protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hhip Human Ortholog
No data available
Associated With hhip Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Domain IPR012938 Glucose/Sorbosone dehydrogenase
Homologous_superfamily IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase
Homologous_superfamily IPR011042 Six-bladed beta-propeller, TolB-like
Domain Details Per Protein
Protein Length EGF-like domain Glucose/Sorbosone dehydrogenase Six-bladed beta-propeller, TolB-like Soluble quinoprotein glucose/sorbosone dehydrogenase
UniProtKB:A0A2R8Q4T0 672
UniProtKB:A7X2Z0 693
UniProtKB:A0A2R8PZ08 672
UniProtKB:A0A0B5JK82 693
UniProtKB:A1A5I0 693
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations