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ZIRC
ZFIN ID: ZDB-GENE-030131-4605
Gene Name: vascular endothelial growth factor Ab
Gene Symbol: vegfab    Nomenclature History

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Previous Names: fd42e02 (1), si:dkey-14d8.3, wu:fd42e02

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor 1 binding activity. Involved in phosphorylation and sprouting angiogenesis. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; hematologic cancer (multiple); hypertension (multiple); reproductive organ cancer (multiple); and retinal disease (multiple). Is expressed in nervous system; pronephros; and vasculature. Orthologous to human VEGFA (vascular endothelial growth factor A).
Genome Resources: Alliance (1),  Gene:558154 (1),  Ensembl(GRCz11):ENSDARG00000034700 (2)
GENE EXPRESSION
All Expression Data: 17 figures from 14 publications
Wild-type Stages, Structures: Segmentation:10-13 somites (14.0h-16.0h) to Larval:Day 4 (96.0h-120.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns92 Insertion Exon 2 Premature Stop CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-vegfab N/A 9
MO2-vegfab N/A 1
MO3-vegfab N/A 1
MO4-vegfab N/A 1
DISEASE ASSOCIATED WITH vegfab HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Microvascular complications of diabetes 1} 603933
DISEASE ASSOCIATED WITH vegfab VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Cellular Component integral component of membrane (more)
Molecular Function protein binding (more)
GO Terms (all 20)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA vegfab-201 (1)    Ensembl 600
vegfab-202 (1)    Ensembl 2198
vegfab-203 (1)    Ensembl 2227
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM vegfab No data available
MARKER RELATIONSHIPS
vegfab Contained in: [BAC] DKEY-14D8 (1) (order this)
vegfab Encodes: [EST] fd42e02
[cDNA] MGC:162743 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001044855 (1) 2814 bp
Genomic GenBank:BX324164 (1) 264155 bp Blast at MegaBLAST
Polypeptide UniProtKB:F1QDN7 (1) 251 aa
Sequence Clusters UniGene:79865 (1)
Sequence Information (all 31)
ORTHOLOGY for vegfab ( Chr: 4 )
CITATIONS (78)