Gene

vegfab

ID
ZDB-GENE-030131-4605
Name
vascular endothelial growth factor Ab
Symbol
vegfab Nomenclature History
Previous Names
  • fd42e02 (1)
  • si:dkey-14d8.3
  • wu:fd42e02
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor 1 binding activity. Involved in phosphorylation and sprouting angiogenesis. Predicted to localize to extracellular space. Is expressed in nervous system; pronephros; and vasculature. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); hypertension (multiple); and retinal disease (multiple). Orthologous to human VEGFA (vascular endothelial growth factor A).
Genome Resources
Note
None
Expression
All Expression Data
19 figures from 16 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vegfab Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Microvascular complications of diabetes 1} 603933
Associated With vegfab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023581 Platelet-derived growth factor, conserved site
Domain IPR000072 PDGF/VEGF domain
Domain IPR027928 Vascular endothelial growth factor, heparin-binding domain
Homologous_superfamily IPR029034 Cystine-knot cytokine
Homologous_superfamily IPR036841 Vascular endothelial growth factor, heparin-binding domain superfamily
Domain Details Per Protein
Protein Length Cystine-knot cytokine PDGF/VEGF domain Platelet-derived growth factor, conserved site Vascular endothelial growth factor, heparin-binding domain Vascular endothelial growth factor, heparin-binding domain superfamily
UniProtKB:F1QTG5 146
UniProtKB:Q5RHW5 228
UniProtKB:F1QDN7 251
UniProtKB:Q1ANK8 233
UniProtKB:Q1ECU5 250
UniProtKB:A4VCG6 194
UniProtKB:Q0QYI0 194
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations