Gene
etfa
- ID
- ZDB-GENE-030131-4449
- Name
- electron transfer flavoprotein subunit alpha
- Symbol
- etfa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have electron transfer activity and flavin adenine dinucleotide binding activity. Involved in animal organ morphogenesis; mitochondrion morphogenesis; and regulation of fatty acid beta-oxidation. Used to study multiple acyl-CoA dehydrogenase deficiency. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Is expressed in several structures, including alar plate midbrain region; digestive system; musculature system; nervous system; and yolk syncytial layer. Orthologous to human ETFA (electron transfer flavoprotein subunit alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1020 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| multiple acyl-CoA dehydrogenase deficiency | Alliance | Glutaric acidemia IIA | 231680 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| multiple acyl-CoA dehydrogenase deficiency | etfavu463/vu463 | standard conditions | Kim et al., 2013 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018206 | Electron transfer flavoprotein subunit alpha, conserved site |
| Domain | IPR014730 | Electron transfer flavoprotein, alpha/beta-subunit, N-terminal |
| Domain | IPR014731 | Electron transfer flavoprotein, alpha subunit, C-terminal |
| Domain | IPR033947 | Electron transfer flavoprotein, alpha subunit, N-terminal |
| Family | IPR001308 | Electron transfer flavoprotein alpha subunit/FixB |
| Homologous_superfamily | IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold |
| Homologous_superfamily | IPR029035 | DHS-like NAD/FAD-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | DHS-like NAD/FAD-binding domain superfamily | Electron transfer flavoprotein, alpha/beta-subunit, N-terminal | Electron transfer flavoprotein, alpha subunit, C-terminal | Electron transfer flavoprotein alpha subunit/FixB | Electron transfer flavoprotein, alpha subunit, N-terminal | Electron transfer flavoprotein subunit alpha, conserved site | Rossmann-like alpha/beta/alpha sandwich fold |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZUS9
|
333 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available