Gene
setb
- ID
- ZDB-GENE-030131-433
- Name
- SET nuclear proto-oncogene b
- Symbol
- setb Nomenclature History
- Previous Names
-
- wu:fb30g11
- wu:fd16c08
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable chromatin binding activity and histone binding activity. Acts upstream of or within neuromast development and somitogenesis. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including digestive system; nervous system; optic cup; otic vesicle; and tail bud. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to several human genes including SET (SET nuclear proto-oncogene).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder, autosomal dominant 58 | 618106 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NAP-like superfamily | Nucleosome assembly protein (NAP) |
|---|---|---|---|
|
UniProtKB:Q6TGU0
|
275 | ||
|
UniProtKB:A0A8M2B801
|
268 |
Interactions and Pathways
No data available
Plasmids
No data available