Gene

chrng

ID
ZDB-GENE-030131-3805
Name
cholinergic receptor, nicotinic, gamma
Symbol
chrng Nomenclature History
Previous Names
  • chrngl
  • AChr gamma (1)
  • wu:fc54e06
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Contributes to acetylcholine receptor activity. Involved in cholinergic synaptic transmission. Localizes to acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in multiple pterygium syndrome. Is expressed in musculature system. Orthologous to human CHRNG (cholinergic receptor nicotinic gamma subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chrng Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
contractures, pterygia, and spondylocarpotarsal fusion syndrome Alliance Escobar syndrome 265000
contractures, pterygia, and spondylocarpotarsal fusion syndrome Alliance Multiple pterygium syndrome, lethal type 253290
Associated With chrng Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018000 Neurotransmitter-gated ion-channel, conserved site
Domain IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
Domain IPR006202 Neurotransmitter-gated ion-channel ligand-binding domain
Family IPR002394 Nicotinic acetylcholine receptor
Family IPR006201 Neurotransmitter-gated ion-channel
Homologous_superfamily IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamily
Homologous_superfamily IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Homologous_superfamily IPR038050 Neuronal acetylcholine receptor
Domain Details Per Protein
Protein Length Neuronal acetylcholine receptor Neurotransmitter-gated ion-channel Neurotransmitter-gated ion-channel, conserved site Neurotransmitter-gated ion-channel ligand-binding domain Neurotransmitter-gated ion-channel ligand-binding domain superfamily Neurotransmitter-gated ion-channel transmembrane domain Neurotransmitter-gated ion-channel transmembrane domain superfamily Nicotinic acetylcholine receptor
UniProtKB:G1FMP9 540
UniProtKB:E7F9V1 540
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-chrne,chrng polyclonal Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations