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ZIRC
ZFIN ID: ZDB-GENE-030131-3375
Gene Name: AUP1 lipid droplet regulating VLDL assembly factor
Gene Symbol: aup1    Nomenclature History

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Previous Names: wu:fc37d06, zgc:77755

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have ubiquitin binding activity and ubiquitin-protein transferase activator activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to localize to the Hrd1p ubiquitin ligase ERAD-L complex and integral component of endoplasmic reticulum membrane. Orthologous to human AUP1 (AUP1 lipid droplet regulating VLDL assembly factor).
Genome Resources: Alliance (1),  Gene:324654 (1),  Ensembl(GRCz11):ENSDARG00000092609 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:73323]
  1 figure (1 image) from Thisse et al., 2004 [MGC:77755]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012637Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la019101Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH aup1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH aup1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ubiquitin-dependent ERAD pathway (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function ubiquitin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003892 (1)
  • PROSITE:PS51140 (1)
  • Pfam:PF02845 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript aup1-202 (1)    Ensembl 865
    mRNA aup1-201 (1)    Ensembl 1866
    ncRNA aup1-004 (1)    Ensembl 879
    aup1-005 (1)    Ensembl 455
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aup1 No data available
    MARKER RELATIONSHIPS
    aup1 Contained in: [BAC] CH73-305J1 (1) (order this)
    aup1 Encodes: [EST] fc37d06
    [cDNA] MGC:73323 (1) (order this), MGC:77755 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199690 (1) 1836 bp
    Genomic GenBank:FP085432 (1) 119093 bp
    Select Tool
    Polypeptide UniProtKB:Q6PBN5 (1) 423 aa
    Sequence Clusters UniGene:2621 (1)
    Sequence Information (all 19)
    ORTHOLOGY for aup1 ( Chr: 14 )
    CITATIONS (26)