Gene

fstl1b

ID
ZDB-GENE-030131-3029
Name
follistatin-like 1b
Symbol
fstl1b Nomenclature History
Previous Names
  • fstl2 (1)
  • fa95c03
  • fc25c04
  • wu:fa95c03
  • wu:fc25c04
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable calcium ion binding activity and heparin binding activity. Acts upstream of or within dorsal/ventral pattern formation; notochord cell differentiation; and regulation of BMP signaling pathway. Predicted to be active in extracellular region. Is expressed in several structures, including axis; central nervous system; fin; head mesenchyme; and mesoderm. Orthologous to human FSTL1 (follistatin like 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
22 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa1267Allele with one point mutationUnknownSplice SiteENU
sa21439Allele with one point mutationUnknownPremature StopENU
sa34567Allele with one point mutationUnknownSplice SiteENU
sa44701Allele with one point mutationUnknownUnknownENU
y345EtTransgenic insertionUnknownUnknownDNA
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Sequence Targeting Reagents
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Human Disease
Associated With fstl1b Human Ortholog
No data available
Associated With fstl1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002048 EF-hand domain
Domain IPR002350 Kazal domain
Domain IPR003645 Follistatin-like, N-terminal
Domain IPR015369 Follistatin/Osteonectin EGF domain
Family IPR050653 Protease Inhibitors and Growth Factor Antagonists
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Domain Details Per Protein
Protein Length EF-hand domain EF-hand domain pair Follistatin-like, N-terminal Follistatin/Osteonectin EGF domain Kazal domain Kazal domain superfamily Protease Inhibitors and Growth Factor Antagonists
UniProtKB:A0A8M3BCA5 309
UniProtKB:Q2PMI2 310
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 9
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA fstl1b-201 (1) Ensembl 4,711 nt
ncRNA fstl1b-002 (1) Ensembl 1,166 nt
ncRNA fstl1b-003 (1) Ensembl 755 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-21F1ZFIN Curated Data
Contained inBACDKEY-32O22ZFIN Curated Data
Contained inFosmidCH1073-394I4ZFIN Curated Data
ContainsSNPrs3728210
    ZFIN Curated Data
    EncodesESTfa95c03
    EncodesESTfc25c04
    EncodesESTIMAGE:7154772Thisse et al., 2004
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanFSTL13
    Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    MouseFstl116
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    Citations
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