Gene

fstl1b

ID

ZDB-GENE-030131-3029

Name

follistatin-like 1b

Symbol

fstl1b Nomenclature History

Previous Names

fstl2 (1)
fa95c03
fc25c04
wu:fa95c03
wu:fc25c04

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to enable calcium ion binding activity and heparin binding activity. Acts upstream of or within dorsal/ventral pattern formation; notochord cell differentiation; and regulation of BMP signaling pathway. Predicted to be active in extracellular region. Is expressed in several structures, including axis; central nervous system; fin; head mesenchyme; and mesoderm. Orthologous to human FSTL1 (follistatin like 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

22 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7154772 (14 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fstl1b Human Ortholog

No data available

Associated With fstl1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002048	EF-hand domain
Domain	IPR002350	Kazal domain
Domain	IPR003645	Follistatin-like, N-terminal
Domain	IPR015369	Follistatin/Osteonectin EGF domain
Family	IPR050653	Protease Inhibitors and Growth Factor Antagonists
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR036058	Kazal domain superfamily

Domain Details Per Protein

Protein	Length	EF-hand domain	EF-hand domain pair	Follistatin-like, N-terminal	Follistatin/Osteonectin EGF domain	Kazal domain	Kazal domain superfamily	Protease Inhibitors and Growth Factor Antagonists
UniProtKB:A0A8M3BCA5 InterPro	309
UniProtKB:Q2PMI2 InterPro	310

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fstl1b-201 (1) Ensembl	Ensembl	4,711 nt	Select Tool ZFIN BLAST
ncRNA	fstl1b-002 (1) Ensembl	Ensembl	1,166 nt	Select Tool ZFIN BLAST
ncRNA	fstl1b-003 (1) Ensembl	Ensembl	755 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations