ZFIN is now using GRCz12tu for Genomic Data
Gene
fstl1b
- ID
- ZDB-GENE-030131-3029
- Name
- follistatin-like 1b
- Symbol
- fstl1b Nomenclature History
- Previous Names
-
- fstl2 (1)
- fa95c03
- fc25c04
- wu:fa95c03
- wu:fc25c04
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium ion binding activity and heparin binding activity. Acts upstream of or within dorsal/ventral pattern formation; notochord cell differentiation; and regulation of BMP signaling pathway. Predicted to be active in extracellular region. Is expressed in several structures, including axis; central nervous system; fin; head mesenchyme; and mesoderm. Orthologous to human FSTL1 (follistatin like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 25 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7154772 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Guggeri et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002048 | EF-hand domain |
| Domain | IPR002350 | Kazal domain |
| Domain | IPR003645 | Follistatin-like, N-terminal |
| Domain | IPR015369 | Follistatin/Osteonectin EGF domain |
| Family | IPR050653 | Protease Inhibitors and Growth Factor Antagonists |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR036058 | Kazal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | EF-hand domain | EF-hand domain pair | Follistatin-like, N-terminal | Follistatin/Osteonectin EGF domain | Kazal domain | Kazal domain superfamily | Protease Inhibitors and Growth Factor Antagonists |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3BCA5 | InterPro | 309 | |||||||
| UniProtKB:Q2PMI2 | InterPro | 310 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fstl1b-201
(1)
|
Ensembl | 4,711 nt | ||
| ncRNA |
fstl1b-002
(1)
|
Ensembl | 1,166 nt | ||
| ncRNA |
fstl1b-003
(1)
|
Ensembl | 755 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers