ZFIN is now using GRCz12tu for Genomic Data
Gene
orc6
- ID
- ZDB-GENE-030131-2976
- Name
- origin recognition complex, subunit 6
- Symbol
- orc6 Nomenclature History
- Previous Names
-
- orc6l
- wu:fa94a09
- wu:fc22h10
- zgc:65798
- zgc:77185
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA binding activity. Acts upstream of or within cilium assembly. Predicted to be located in nucleus. Predicted to be part of nuclear origin of replication recognition complex. Is expressed in central nervous system; eye; intermediate cell mass of mesoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 3. Orthologous to human ORC6 (origin recognition complex subunit 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65798 (1 image)
- IMAGE:6907825 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Maerz et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Meier-Gorlin syndrome 3 | Alliance | Meier-Gorlin syndrome 3 | 613803 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | ORC6, first cyclin-like domain | ORC6, second cyclin-like domain | Origin recognition complex, subunit 6, metazoa/plant |
|---|---|---|---|---|---|
| UniProtKB:Q6ZM36 | InterPro | 256 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers