ZFIN is now using GRCz12tu for Genomic Data
Gene
hnf4b
- ID
- ZDB-GENE-030131-2730
- Name
- hepatic nuclear factor 4, beta
- Symbol
- hnf4b Nomenclature History
- Previous Names
-
- fc16g07
- NR2A3 (1)
- wu:fc16g07
- zgc:77387
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in yolk syncytial layer.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77387 (7 images)
- MGC:77387 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Domain | IPR049635 | Hepatocyte nuclear factor 4, ligand-binding domain |
| Domain | IPR049636 | Hepatocyte nuclear factor 4-like, DNA-binding domain |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR050274 | Nuclear hormone receptor family NR2 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Hepatocyte nuclear factor 4, ligand-binding domain | Hepatocyte nuclear factor 4-like, DNA-binding domain | Nuclear hormone receptor | Nuclear hormone receptor family NR2 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0G2KE76 | InterPro | 425 | ||||||||
| UniProtKB:Q6P0E0 | InterPro | 465 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers