ZFIN is now using GRCz12tu for Genomic Data
Gene
cul1a
- ID
- ZDB-GENE-030131-2603
- Name
- cullin 1a
- Symbol
- cul1a Nomenclature History
- Previous Names
-
- wu:fc13a10
- zgc:77500
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ubiquitin ligase complex scaffold activity and ubiquitin protein ligase binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to act upstream of or within non-canonical NF-kappaB signal transduction. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to human CUL1 (cullin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR016157 | Cullin, conserved site |
| Domain | IPR001373 | Cullin, N-terminal |
| Domain | IPR016158 | Cullin homology domain |
| Domain | IPR019559 | Cullin, neddylation domain |
| Domain | IPR059120 | Cullin-like, alpha+beta domain |
| Family | IPR045093 | Cullin |
| Homologous_superfamily | IPR016159 | Cullin repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036317 | Cullin homology domain superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cullin | Cullin, conserved site | Cullin homology domain | Cullin homology domain superfamily | Cullin-like, alpha+beta domain | Cullin, neddylation domain | Cullin, N-terminal | Cullin repeat-like-containing domain superfamily | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NYS3 | InterPro | 777 | ||||||||||
| UniProtKB:A0AC58GFA4 | InterPro | 777 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers