Gene

stx4

ID

ZDB-GENE-030131-2455

Name

syntaxin 4

Symbol

stx4 Nomenclature History

Previous Names

si:dkey-220f10.3
wu:fc08c10
zgc:56272 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to enable SNAP receptor activity and SNARE binding activity. Acts upstream of or within detection of mechanical stimulus; response to auditory stimulus; and startle response. Predicted to be located in membrane. Predicted to be part of SNARE complex. Predicted to be active in endomembrane system and plasma membrane. Is expressed in cardiac muscle cell. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness. Orthologous to human STX4 (syntaxin 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6901547 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With stx4 Human Ortholog

No data available

Associated With stx4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR006012	Syntaxin/epimorphin, conserved site
Domain	IPR000727	Target SNARE coiled-coil homology domain
Domain	IPR006011	Syntaxin, N-terminal domain
Family	IPR045242	Syntaxin
Homologous_superfamily	IPR010989	SNARE