Gene
prickle1b
- ID
- ZDB-GENE-030131-2152
- Name
- prickle homolog 1b
- Symbol
- prickle1b Nomenclature History
- Previous Names
-
- fb98c11
- pk1b (1)
- si:ch211-155a11.1
- wu:fb98c11
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable zinc ion binding activity. Acts upstream of with a positive effect on motor neuron migration. Acts upstream of or within nervous system development and neural crest cell migration. Predicted to be located in endomembrane system and membrane. Is expressed in several structures, including mesoderm; myotome; nervous system; neuroepithelial cell; and pharyngeal arch. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Orthologous to human PRICKLE1 (prickle planar cell polarity protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu2482 (25 images)
Wild Type Expression Summary
- All Phenotype Data
- 20 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| progressive myoclonus epilepsy 1B | Alliance | Epilepsy, progressive myoclonic 1B | 612437 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | LIM1 prickle | LIM2 prickle | LIM3 prickle | PET domain | PET prickle | Prickle/Espinas/Testin | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F2Z4V3
|
872 | |||||||
|
UniProtKB:Q5SP54
|
863 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prickle1b-201
(1)
|
Ensembl | 3,335 nt | ||
| mRNA |
prickle1b-202
(1)
|
Ensembl | 922 nt | ||
| mRNA |
prickle1b-203
(1)
|
Ensembl | 3,389 nt |
Interactions and Pathways
No data available
Plasmids
No data available