Gene
prickle1b
- ID
- ZDB-GENE-030131-2152
- Name
- prickle homolog 1b
- Symbol
- prickle1b Nomenclature History
- Previous Names
-
- fb98c11
- pk1b (1)
- si:ch211-155a11.1
- wu:fb98c11
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have zinc ion binding activity. Involved in facial nucleus development; hindbrain tangential cell migration; and motor neuron migration. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Is expressed in several structures, including mesoderm; myotome; nervous system; neuroepithelial cell; and pharyngeal arch. Orthologous to human PRICKLE1 (prickle planar cell polarity protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu2482 (25 images)
Wild Type Expression Summary
- All Phenotype Data
- 20 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| progressive myoclonus epilepsy 1B | Alliance | Epilepsy, progressive myoclonic 1B | 612437 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | LIM1 prickle | LIM2 prickle | LIM3 prickle | PET domain | PET prickle | Prickle/Espinas/Testin | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F2Z4V3
|
872 | |||||||
|
UniProtKB:Q5SP54
|
863 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prickle1b-201
(1)
|
Ensembl | 3,335 nt | ||
| mRNA |
prickle1b-202
(1)
|
Ensembl | 922 nt | ||
| mRNA |
prickle1b-203
(1)
|
Ensembl | 3,389 nt |
Interactions and Pathways
No data available
Plasmids
No data available