Gene

fignl1

ID

ZDB-GENE-030131-1862

Name

fidgetin-like 1

Symbol

fignl1 Nomenclature History

Previous Names

fb82h05
wu:fb82h05 (1)
wu:fj99a11
zgc:193664

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have microtubule-severing ATPase activity. Predicted to be involved in cytoplasmic microtubule organization and regulation of double-strand break repair via homologous recombination. Predicted to localize to nucleus. Is expressed in head; nervous system; neural tube; tail bud; and vertical myoseptum. Orthologous to human FIGNL1 (fidgetin like 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fignl1 Human Ortholog

No data available

Associated With fignl1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003960	ATPase, AAA-type, conserved site
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR003959	ATPase, AAA-type, core
Domain	IPR015415	Spastin/Vps4, C-terminal
Domain	IPR041569	AAA ATPase, AAA+ lid domain
Domain	IPR047858	Fidgetin-like 1, ATPase domain
Family	IPR050304	Microtubule-severing AAA ATPase
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase