Gene
map2k5
- ID
- ZDB-GENE-030131-1517
- Name
- mitogen-activated protein kinase kinase 5
- Symbol
- map2k5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have MAP kinase kinase activity and protein serine/threonine kinase activity. Involved in brain development. Predicted to localize to cytoplasm. Is expressed in spinal cord. Orthologous to human MAP2K5 (mitogen-activated protein kinase kinase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Jo et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Schulte et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000270 | PB1 domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR034851 | Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain |
| Domain | IPR053793 | PB1-like domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain | PB1 domain | PB1-like domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3BB07
|
400 | |||||||
|
UniProtKB:B1NA67
|
449 | |||||||
|
UniProtKB:A9JRD0
|
450 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map2k5-201
(1)
|
Ensembl | 4,512 nt |
Interactions and Pathways
No data available
Plasmids
No data available