Gene

smc2

ID
ZDB-GENE-030131-105
Name
structural maintenance of chromosomes 2
Symbol
smc2 Nomenclature History
Previous Names
  • fb92e05
  • hm:zeh1628
  • wu:fb92e05 (1)
  • zeh1628
  • zgc:55326 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have ATP binding activity. Predicted to be involved in chromosome organization. Predicted to localize to chromosome and nucleus. Is expressed in several structures, including blood vessel; digestive system; nervous system; optic vesicle; and pectoral fin. Orthologous to human SMC2 (structural maintenance of chromosomes 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from Li et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With smc2 Human Ortholog
No data available
Associated With smc2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003395 RecF/RecN/SMC, N-terminal
Domain IPR010935 SMCs flexible hinge
Domain IPR027120 Smc2, ATP-binding cassette domain
Family IPR024704 Structural maintenance of chromosomes protein
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036277 SMCs flexible hinge superfamily
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase RecF/RecN/SMC, N-terminal Smc2, ATP-binding cassette domain SMCs flexible hinge SMCs flexible hinge superfamily Structural maintenance of chromosomes protein
UniProtKB:B8A5K9 1199
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA smc2-201 (1) Ensembl 4,073 nt
ncRNA smc2-002 (1) Ensembl 441 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations