Gene

gapdh

ID
ZDB-GENE-030115-1
Name
glyceraldehyde-3-phosphate dehydrogenase
Symbol
gapdh Nomenclature History
Previous Names
  • gapd (1)
  • bb02e05
  • cb609 (1)
  • mg:bb02e05
  • wu:fb33a10
  • wu:ft80f05
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; microtubule binding activity; and peptidyl-cysteine S-nitrosylase activity. Predicted to be involved in several processes, including glycolytic process; peptidyl-cysteine S-trans-nitrosylation; and protein stabilization. Predicted to act upstream of or within apoptotic process and glucose metabolic process. Predicted to be located in cytoplasm; microtubule cytoskeleton; and nucleus. Predicted to be active in cytosol. Is expressed in several structures, including cardiovascular system; integument; musculature system; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDH (glyceraldehyde-3-phosphate dehydrogenase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
43 figures from 32 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gapdh Human Ortholog
No data available
Associated With gapdh Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site
Domain IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
Domain IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
Family IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I
Family IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length Glyceraldehyde 3-phosphate dehydrogenase, active site Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain Glyceraldehyde-3-phosphate dehydrogenase, type I Glyceraldehyde/Erythrose phosphate dehydrogenase family NAD(P)-binding domain superfamily
UniProtKB:Q5XJ10 333
UniProtKB:E9QIH5 239
UniProtKB:E9QGA9 223
UniProtKB:E9QCY9 53
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab6-gapdh polyclonal Rabbit
GeneTex
2
Ab1-gapdh monoclonal Mouse
  • WB
Abcam plc
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations