Gene

hspd1

ID
ZDB-GENE-021206-1
Name
heat shock 60 protein 1
Symbol
hspd1 Nomenclature History
Previous Names
  • hsp60 (1)
  • cb863 (1)
  • cpn60 (1)
  • fa04a05
  • fb22d10
  • fi27b05
  • id:ibd2197
  • nbl (1)
  • no blastema (1)
  • sb:cb144 (1)
  • wu:fa04a05
  • wu:fb22d10
  • wu:fi04a12
  • wu:fi27b05
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have chaperone binding activity. Involved in fin regeneration; regulation of cell population proliferation; and regulation of neutrophil chemotaxis. Localizes to mitochondrial matrix. Is expressed in several structures, including anterior neural keel; digestive system; mesoderm; musculature system; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autistic disorder; glucose intolerance; hereditary spastic paraplegia (multiple); and hypomyelinating leukodystrophy 4. Orthologous to human HSPD1 (heat shock protein family D (Hsp60) member 1).
Genome Resources
Note
None
Expression
All Expression Data
34 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hspd1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary spastic paraplegia 13 Alliance Spastic paraplegia 13, autosomal dominant 605280
hypomyelinating leukodystrophy 4 Alliance Leukodystrophy, hypomyelinating, 4 612233
Associated With hspd1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018370 Chaperonin Cpn60, conserved site
Family IPR001844 Chaperonin Cpn60
Family IPR002423 Chaperonin Cpn60/TCP-1 family
Homologous_superfamily IPR027409 GroEL-like apical domain superfamily
Homologous_superfamily IPR027410 TCP-1-like chaperonin intermediate domain superfamily
Homologous_superfamily IPR027413 GroEL-like equatorial domain superfamily
Domain Details Per Protein
Protein Length Chaperonin Cpn60 Chaperonin Cpn60, conserved site Chaperonin Cpn60/TCP-1 family GroEL-like apical domain superfamily GroEL-like equatorial domain superfamily TCP-1-like chaperonin intermediate domain superfamily
UniProtKB:Q8JGM5 309
UniProtKB:Q803B0 575
UniProtKB:Q8JGM6 73
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations