ZFIN is now using GRCz12tu for Genomic Data
Gene
nav3
- ID
- ZDB-GENE-021205-1
- Name
- neuron navigator 3
- Symbol
- nav3 Nomenclature History
- Previous Names
-
- cb419 (1)
- wu:fa05f06
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables actin binding activity. Acts upstream of or within heart formation; liver morphogenesis; and pancreas development. Located in Golgi apparatus; filopodium; and lamellipodium. Is expressed in several structures, including cardiovascular system; digestive system; liver primordium; nervous system; and periderm. Human ortholog(s) of this gene implicated in opiate dependence. Orthologous to human NAV3 (neuron navigator 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb419 (27 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001715 | Calponin homology domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR057126 | Neuron navigator 1-like, ubiquitin-like domain |
| Domain | IPR057568 | CortBP2/NAV1-like, AAA+ ATPase lid domain |
| Family | IPR039041 | Nav/unc-53 family |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers