ZFIN is now using GRCz12tu for Genomic Data
Gene
nav3
- ID
- ZDB-GENE-021205-1
- Name
- neuron navigator 3
- Symbol
- nav3 Nomenclature History
- Previous Names
-
- cb419 (1)
- wu:fa05f06
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables actin binding activity. Acts upstream of or within heart formation; liver morphogenesis; and pancreas development. Located in Golgi apparatus; filopodium; and lamellipodium. Is expressed in several structures, including cardiovascular system; digestive system; liver primordium; nervous system; and periderm. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with poor or absent speech, dysmorphic facies, and behavioral abnormalities and opiate dependence. Orthologous to human NAV3 (neuron navigator 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb419 (27 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001715 | Calponin homology domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR057126 | Neuron navigator 1-like, ubiquitin-like domain |
| Domain | IPR057568 | CortBP2/NAV1-like, AAA+ ATPase lid domain |
| Family | IPR039041 | Nav/unc-53 family |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers