ZFIN is now using GRCz12tu for Genomic Data
Gene
reln
- ID
- ZDB-GENE-020822-1
- Name
- reelin
- Symbol
- reln Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable lipoprotein particle receptor binding activity. Acts upstream of or within cerebellar Purkinje cell layer morphogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space and neuron projection. Is expressed in immature eye and nervous system. Human ortholog(s) of this gene implicated in Norman-Roberts syndrome; autistic disorder; familial temporal lobe epilepsy 7; and schizophrenia. Orthologous to human RELN (reelin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 16 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial temporal lobe epilepsy 7 | Alliance | {Epilepsy, familial temporal lobe, 7} | 616436 |
| Norman-Roberts syndrome | Alliance | Lissencephaly 2 (Norman-Roberts type) | 257320 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like domain | Reeler domain | Reeler domain superfamily | Reelin | Reelin, subrepeat B | Sialidase superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:G1BJ50 | InterPro | 3468 | ||||||
| UniProtKB:A0AB32TAK6 | InterPro | 1027 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers