Gene

reln

ID
ZDB-GENE-020822-1
Name
reelin
Symbol
reln Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have lipoprotein particle receptor binding activity. Involved in cerebellar Purkinje cell layer morphogenesis. Is expressed in immature eye and nervous system. Human ortholog(s) of this gene implicated in Norman-Roberts syndrome; autistic disorder; familial temporal lobe epilepsy 7; and schizophrenia. Orthologous to human RELN (reelin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
15 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With reln Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial temporal lobe epilepsy 7 Alliance {Epilepsy, familial temporal lobe, 7} 616436
Norman-Roberts syndrome Alliance Lissencephaly 2 (Norman-Roberts type) 257320
Associated With reln Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Domain IPR002861 Reeler domain
Domain IPR013111 EGF-like domain, extracellular
Domain IPR041161 Tenascin, EGF-like domain
Family IPR034968 Reelin
Homologous_superfamily IPR008979 Galactose-binding-like domain superfamily
Homologous_superfamily IPR036278 Sialidase superfamily
Homologous_superfamily IPR042307 Reeler domain superfamily
Domain Details Per Protein
Protein Length EGF-like domain EGF-like domain, extracellular Galactose-binding-like domain superfamily Reeler domain Reeler domain superfamily Reelin Sialidase superfamily Tenascin, EGF-like domain
UniProtKB:G1BJ50 3468
UniProtKB:Q8AXK7 1078
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-reln monoclonal IgG1 Mouse
  • IHC
  • WB
Millipore
6
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations