ZFIN is now using GRCz12tu for Genomic Data
Gene
reln
- ID
- ZDB-GENE-020822-1
- Name
- reelin
- Symbol
- reln Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable lipoprotein particle receptor binding activity. Acts upstream of or within cerebellar Purkinje cell layer morphogenesis. Predicted to be active in extracellular matrix; extracellular space; and neuron projection. Is expressed in immature eye and nervous system. Human ortholog(s) of this gene implicated in Norman-Roberts syndrome; autistic disorder; familial temporal lobe epilepsy 7; and schizophrenia. Orthologous to human RELN (reelin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 25 figures from 18 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 16 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial temporal lobe epilepsy 7 | Alliance | {Epilepsy, familial temporal lobe, 7} | 616436 |
| Norman-Roberts syndrome | Alliance | Lissencephaly 2 (Norman-Roberts type) | 257320 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like domain | Reeler domain | Reeler domain superfamily | Reelin | Reelin, subrepeat B | Sialidase superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:G1BJ50 | InterPro | 3468 | ||||||
| UniProtKB:A0AB32TAK6 | InterPro | 1027 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers