Gene
reln
- ID
- ZDB-GENE-020822-1
- Name
- reelin
- Symbol
- reln Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have lipoprotein particle receptor binding activity. Predicted to be involved in central nervous system development and neuron migration. Human ortholog(s) of this gene implicated in Norman-Roberts syndrome; autistic disorder; familial temporal lobe epilepsy 7; and schizophrenia. Is expressed in immature eye and nervous system. Orthologous to human RELN (reelin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial temporal lobe epilepsy 7 | Alliance | {Epilepsy, familial temporal lobe, 7} | 616436 |
| Norman-Roberts syndrome | Alliance | Lissencephaly 2 (Norman-Roberts type) | 257320 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR002861 | Reeler domain |
| Domain | IPR041161 | Tenascin, EGF-like domain |
| Family | IPR034968 | Reelin |
| Homologous_superfamily | IPR036278 | Sialidase superfamily |
| Homologous_superfamily | IPR042307 | Reeler domain superfamily |
| Repeat | IPR049419 | Reelin, subrepeat B |
Domain Details Per Protein
| Protein | Length | EGF-like domain | Reeler domain | Reeler domain superfamily | Reelin | Reelin, subrepeat B | Sialidase superfamily | Tenascin, EGF-like domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:G1BJ50
|
3468 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available