Gene
caspb
- ID
- ZDB-GENE-020812-1
- Name
- caspase b
- Symbol
- caspb Nomenclature History
- Previous Names
-
- caspy2
- casp19a (1)
- zgc:109807
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Exhibits cysteine-type endopeptidase activity; enzyme activator activity; and lipopolysaccharide binding activity. Involved in defense response to bacterium; positive regulation of apoptotic process; and pyroptosis. Predicted to localize to cytoplasm. Is expressed in several structures, including digestive system; heart; immune system; integument; and muscle. Orthologous to human CASP4 (caspase 4) and CASP5 (caspase 5).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109807 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR016129 | Peptidase family C14A, His active site |
Active_site | IPR033139 | Peptidase family C14A, cysteine active site |
Domain | IPR001309 | Peptidase C14, p20 domain |
Domain | IPR002138 | Peptidase C14, caspase non-catalytic subunit p10 |
Domain | IPR004020 | DAPIN domain |
Domain | IPR011600 | Peptidase C14, caspase domain |
Domain | IPR015917 | Peptidase C14A, caspase catalytic domain |
Homologous_superfamily | IPR011029 | Death-like domain superfamily |
Homologous_superfamily | IPR029030 | Caspase-like domain superfamily |
Domain Details Per Protein
Protein | Length | Caspase-like domain superfamily | DAPIN domain | Death-like domain superfamily | Peptidase C14A, caspase catalytic domain | Peptidase C14, caspase domain | Peptidase C14, caspase non-catalytic subunit p10 | Peptidase C14, p20 domain | Peptidase family C14A, cysteine active site | Peptidase family C14A, His active site |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q504J1
|
404 |
Interactions and Pathways
No data available
Plasmids
No data available