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ZIRC
ZFIN ID: ZDB-GENE-020712-1
Gene Name: membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
Gene Symbol: mpp5a    Nomenclature History

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Previous Names: mpp5, nagie oko, nok

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Involved in several processes, including animal organ development; apical protein localization; and morphogenesis of an epithelium. Localizes to several cellular components, including the apical junction complex; intrinsic component of plasma membrane; and photoreceptor inner segment. Is expressed in several structures, including EVL; brain; eye; neural tube; and photoreceptor cell. Orthologous to human MPP5 (membrane palmitoylated protein 5).
Genome Resources: Alliance (1),  Gene:252845 (1),  Ensembl(GRCz11):ENSDARG00000006272 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2226Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • jj2 Translocation Unknown Unknown G_RAYS
    m227 Point Mutation Unknown Missense ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m520 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • rw161 Unknown Unknown Unknown
    rw464 Unknown Unknown Unknown
    s305 Unknown Unknown Unknown
    sa2908 Point Mutation Unknown Splice Site ENU
    sa15209 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36468 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • wi83Tg Transgenic Insertion Unknown Unknown DNA
    zju203 Complex Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-mpp5a 1
    MO1-mpp5a N/A 4
    MO2-mpp5a N/A 1
    MO3-mpp5a N/A 1
    MO4-mpp5a N/A 1
    MO5-mpp5a N/A 1
    MO6-mpp5a N/A 2
    PHENOTYPE
    Data: 41 figures from 23 publications
    Observed in:
    DISEASE ASSOCIATED WITH mpp5a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mpp5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process apical protein localization (more)
    Cellular Component apical junction complex (more)
    Molecular Function ATP binding (more)
    GO Terms (all 31)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mpp5a-202 (1)    Ensembl 2903
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-mpp5a Rabbit IHC Abdelilah-Seyfried Lab Potsdam
    1
    Ab3-mpp5a polyclonal Rabbit IHC, WB 9
    Ab2-mpp5a polyclonal Rabbit IHC, WB 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mpp5a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(myl7:mpp5a) myl7 mpp5a Danio rerio 1 5
    Tg(Tru.tyr:mpp5a-GFP) GFPmpp5a Danio rerioTakifugu rubripes 1 3
    MARKER RELATIONSHIPS
    mpp5a Contained in: [BAC] CH211-37L23 (1) (order this)
    mpp5a Encodes: [cDNA] MGC:194555 (1) (order this), MGC:194581 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_194363 (1) 3073 bp
    Genomic GenBank:BX005308 (1) 168462 bp
    Select Tool
    Polypeptide UniProtKB:B3DIW9 (1) 703 aa
    Sequence Clusters UniGene:18838 (1)
    Sequence Information (all 23)
    ORTHOLOGY for mpp5a ( Chr: 17 )
    CITATIONS (76)