Gene

ahr1a

ID
ZDB-GENE-020531-2
Name
aryl hydrocarbon receptor 1a
Symbol
ahr1a Nomenclature History
Previous Names
  • ahr1
  • AHR2 (1)
  • ahra
  • zfAHR1
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have DNA binding activity; DNA-binding transcription factor activity; and protein dimerization activity. Involved in cellular response to organic cyclic compound. Predicted to localize to cytoplasm; nucleus; and transcription factor complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Is expressed in brain; heart; liver; and pleuroperitoneal region. Orthologous to human AHR (aryl hydrocarbon receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Seifinejad et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ahr1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 85 Alliance ?Retinitis pigmentosa 85 618345
Associated With ahr1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000014 PAS domain
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Domain IPR013655 PAS fold-3
Domain IPR013767 PAS fold
Family IPR001067 Nuclear translocator
Family IPR033348 Aryl hydrocarbon receptor
Family IPR039091 Aryl hydrocarbon receptor/Aryl hydrocarbon receptor repressor
Homologous_superfamily IPR035965 PAS domain superfamily
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Repeat IPR001610 PAC motif
Domain Details Per Protein
Protein Length Aryl hydrocarbon receptor Aryl hydrocarbon receptor/Aryl hydrocarbon receptor repressor Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Nuclear translocator PAC motif PAS domain PAS domain superfamily PAS fold PAS fold-3
UniProtKB:O57569 184
UniProtKB:F1RBN7 790
UniProtKB:Q8QGQ3 805
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations