Gene

id3

ID

ZDB-GENE-020515-1

Name

inhibitor of DNA binding 3

Symbol

id3 Nomenclature History

Previous Names

etID138038.17 (1)
fa56g03
Id2d (1)
ik:tdsubc_2g3 (1)
tdsubc_2g3
wu:fa56g03 (1)
xx:tdsubc_2g3

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable transcription corepressor activity. Acts upstream of or within dopaminergic neuron differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including digestive system; germ ring; nervous system; polster; and presumptive ectoderm. Orthologous to human ID3 (inhibitor of DNA binding 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

21 figures from 11 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6899625 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With id3 Human Ortholog

No data available

Associated With id3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Family	IPR026052	DNA-binding protein inhibitor
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily