Gene

gbx2

ID
ZDB-GENE-020509-2
Name
gastrulation brain homeobox 2
Symbol
gbx2 Nomenclature History
Previous Names
  • gbx-2 (1)
  • fd07f12
  • wu:fd07f12 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in cerebellum development; iridophore differentiation; and telencephalon regionalization. Predicted to localize to nucleus. Is expressed in several structures, including midbrain hindbrain boundary neural keel; midbrain hindbrain boundary neural rod; midbrain neural rod; nervous system; and presumptive rhombomere 1. Orthologous to human GBX2 (gastrulation brain homeobox 2).
Genome Resources
Note
None
Expression
All Expression Data
32 figures from 19 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gbx2 Human Ortholog
No data available
Associated With gbx2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Family IPR031250 Homeobox protein GBX-2
Family IPR042982 Homeobox protein GBX-1/2
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily Homeobox protein GBX-1/2 Homeobox protein GBX-2
UniProtKB:Q8QGU1 342
UniProtKB:Q8AXK9 342
UniProtKB:Q98T83 341
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations