Gene
eef1g
- ID
- ZDB-GENE-020423-3
- Name
- eukaryotic translation elongation factor 1 gamma
- Symbol
- eef1g Nomenclature History
- Previous Names
-
- db03h10
- fk76a09
- mg:db03h10
- nan
- nearly normal
- wu:fk76a09 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to act upstream of or within translation. Predicted to be active in cytoplasm and nucleus. Orthologous to human EEF1G (eukaryotic translation elongation factor 1 gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907809 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001662 | Elongation factor 1B gamma, C-terminal |
| Domain | IPR004045 | Glutathione S-transferase, N-terminal |
| Domain | IPR004046 | Glutathione S-transferase, C-terminal |
| Domain | IPR010987 | Glutathione S-transferase, C-terminal-like |
| Family | IPR040079 | Glutathione transferase family |
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Domain Details Per Protein
| Protein | Length | Elongation factor 1B gamma, C-terminal | Elongation factor EF1B gamma, C-terminal domain superfamily | Elongation Factors and Glutathione S-transferases | Glutathione S-transferase, C-terminal | Glutathione S-transferase, C-terminal domain superfamily | Glutathione S-transferase, C-terminal-like | Glutathione S-transferase, N-terminal | Glutathione transferase family | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q8JIU6
|
442 | |||||||||
|
UniProtKB:Q6PE25
|
442 |
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Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(eef1g:EGFP) |
|
| 1 | (3) |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-171N3 | ZFIN Curated Data | |
| Encodes | EST | db03h10 | ||
| Encodes | EST | fk76a09 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:6907809 | Thisse et al., 2004 | |
| Encodes | EST | zeh1592 | ||
| Encodes | cDNA | MGC:66090 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_173263 (1) | 1485 nt | ||
| Genomic | GenBank:BX571940 (2) | 179550 nt | ||
| Polypeptide | UniProtKB:Q6PE25 (1) | 442 aa |
- Okeke, C., Paulding, D., Riedel, A., Paudel, S., Phelan, C., Teng, C.S., Barske, L. (2022) Control of cranial ectomesenchyme fate by Nr2f nuclear receptors. Development (Cambridge, England). 149(23):
- Nepal, C., Hadzhiev, Y., Balwierz, P., Tarifeño-Saldivia, E., Cardenas, R., Wragg, J.W., Suzuki, A.M., Carninci, P., Peers, B., Lenhard, B., Andersen, J.B., Müller, F. (2020) Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing. Nature communications. 11:168
- Li, Y., Agrawal, I., Gong, Z. (2019) Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene transgenic zebrafish model. Disease models & mechanisms. 12(10):
- Yang, Z., Chen, S., Xue, S., Li, X., Sun, Z., Yang, Y., Hu, X., Geng, T., Cui, H. (2018) Generation of Cas9 transgenic zebrafish and their application in establishing an ERV-deficient animal model. Biotechnology Letters. 40(11-12):1507-1518
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Wu, C.C., Tsai, T.H., Chang, C., Lee, T.T., Lin, C., Cheng, I.H., Sun, M.C., Chuang, Y.J., Chen, B.S. (2014) On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio. PLoS One. 9:e97902
- Cuello, S., Ximénez-Embún, P., Ruppen, I., Schonthaler, H.B., Ashman, K., Madrid, Y., Luque-Garcia, J.L., and Cámara, C. (2012) Analysis of protein expression in developmental toxicity induced by MeHg in zebrafish. The Analyst. 137(22):5302-5311
- Burket, C.T., Montgomery, J.E., Thummel, R., Kassen, S.C., Lafave, M.C., Langenau, D.M., Zon, L.I., and Hyde, D.R. (2008) Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Transgenic Research. 17(2):265-279
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
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