ZFIN ID: ZDB-GENE-020205-1
Gene Name: ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
Gene Symbol: ube4b    Nomenclature History

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Previous Names: UFD2 (1), zgc:109766

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have ubiquitin-ubiquitin ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent ERAD pathway. Predicted to localize to the cytoplasm and nucleus. Is expressed in heart and skeletal muscle. Orthologous to human UBE4B (ubiquitination factor E4B).
Genome Resources: Alliance (1),  Gene:170784 (1),  Ensembl(GRCz11):ENSDARG00000037017 (2)
GENE EXPRESSION
All Expression Data: 2 figures from Mammen et al., 2011
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ube4b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH ube4b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process protein ubiquitination (more)
Cellular Component ubiquitin ligase complex (more)
Molecular Function ubiquitin-protein transferase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR003613 U box domain
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain IPR019474 Ubiquitin conjugation factor E4, core
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ube4b-201 (1)    Ensembl 4712
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ube4b No data available
MARKER RELATIONSHIPS
ube4b Contained in: [BAC] DKEY-259L18 (1) (order this)
ube4b Encodes: [cDNA] MGC:109766 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_194362 (1) 3552 bp
Genomic GenBank:BX571850 (1) 236136 bp Blast at MegaBLAST
Polypeptide UniProtKB:G0ZJH8 (1) 1349 aa
Sequence Information (all 27)
ORTHOLOGY for ube4b ( Chr: 23 )
CITATIONS (20)