Gene
s1pr2
- ID
- ZDB-GENE-020123-2
- Name
- sphingosine-1-phosphate receptor 2
- Symbol
- s1pr2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have sphingosine-1-phosphate receptor activity. Involved in several processes, including embryonic morphogenesis; sensory organ development; and sphingosine-1-phosphate receptor signaling pathway. Predicted to localize to integral component of membrane and plasma membrane. Used to study carcinoma. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 68. Is expressed in several structures, including cardiovascular system; midbrain hindbrain boundary neural rod; midbrain hindbrain boundary neural tube; nervous system; and pleuroperitoneal region. Orthologous to human S1PR2 (sphingosine-1-phosphate receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu461 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 45 figures from 25 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 68 | Alliance | Deafness, autosomal recessive 68 | 610419 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| carcinoma | s1pr2m93/m93 | standard conditions | Gu et al., 2015 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Sphingosine 1-phosphate receptor |
|---|---|---|---|---|
|
UniProtKB:Q9I8K8
|
370 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available