Gene
ptprfa
- ID
- ZDB-GENE-020107-2
- Name
- protein tyrosine phosphatase receptor type Fa
- Symbol
- ptprfa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have protein tyrosine phosphatase activity. Involved in sensory neuron axon guidance. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hyperinsulinism. Is expressed in nervous system; pectoral fin; pharyngeal arch; and somite. Orthologous to human PTPRF (protein tyrosine phosphatase receptor type F).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Breasts and/or nipples, aplasia or hypoplasia of, 2 | 616001 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR000242 | Tyrosine-specific protein phosphatase, PTPase domain |
| Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Family | IPR050713 | Receptor-type Tyrosine-protein Phosphatases/Ushers |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like | Receptor-type Tyrosine-protein Phosphatases/Ushers | Tyrosine-specific protein phosphatase, PTPase domain | Tyrosine-specific protein phosphatases domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PLU1
|
1903 | ||||||||||||||
|
UniProtKB:A0A8M9PZG0
|
1802 | ||||||||||||||
|
UniProtKB:A0A8M9QF59
|
1908 | ||||||||||||||
|
UniProtKB:A0A8M9PZF5
|
1816 | ||||||||||||||
|
UniProtKB:A0A8M9QA39
|
1918 | ||||||||||||||
|
UniProtKB:A0A8M9QF62
|
1806 | ||||||||||||||
|
UniProtKB:A0A8M9Q5Y4
|
1812 | ||||||||||||||
|
UniProtKB:A0A8M9PLU6
|
1808 | ||||||||||||||
|
UniProtKB:H9CWQ2
|
1894 | ||||||||||||||
|
UniProtKB:A0A8M9Q5Y1
|
1912 | ||||||||||||||
|
UniProtKB:A0A8M9PLT7
|
1914 | ||||||||||||||
|
UniProtKB:A0A8M9QA48
|
1791 | ||||||||||||||
|
UniProtKB:A0A8M9QA45
|
1907 | ||||||||||||||
|
UniProtKB:A0A8M9PZE9
|
1914 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptprfa-202
(1)
|
Ensembl | 4,041 nt | ||
| mRNA |
ptprfa-203
(1)
|
Ensembl | 8,712 nt | ||
| mRNA |
ptprfa-204
(1)
|
Ensembl | 5,988 nt | ||
| mRNA |
ptprfa-205
(1)
|
Ensembl | 5,682 nt | ||
| mRNA |
ptprfa-206
(1)
|
Ensembl | 8,750 nt | ||
| mRNA |
ptprfa-207
(1)
|
Ensembl | 8,432 nt | ||
| mRNA |
ptprfa-208
(1)
|
Ensembl | 8,738 nt | ||
| ncRNA |
ptprfa-002
(1)
|
Ensembl | 747 nt |
Interactions and Pathways
No data available
Plasmids