Community Action Needed: Please respond to the NIH RFI
Gene

ywhag1

ID
ZDB-GENE-011115-1
Name
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
Symbol
ywhag1 Nomenclature History
Previous Names
  • ywhag
  • cb47 (1)
  • fd20c02
  • wu:fd20c02
  • wu:fj53d01
  • zgc:73131
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Acts upstream of or within brain development and heart development. Predicted to be located in cytoplasm. Is expressed in head; nervous system; neural tube; otic vesicle; and trigeminal placode. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 56. Orthologous to human YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Komoike et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ywhag1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 56 Alliance Developmental and epileptic encephalopathy 56 617665
Associated With ywhag1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023409 14-3-3 protein, conserved site
Domain IPR023410 14-3-3 domain
Family IPR000308 14-3-3 protein
Homologous_superfamily IPR036815 14-3-3 domain superfamily
Domain Details Per Protein
Protein Length 14-3-3 domain 14-3-3 domain superfamily 14-3-3 protein 14-3-3 protein, conserved site
UniProtKB:Q6PC29 247
UniProtKB:A1E267 247
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations