Gene
sfrp5
- ID
- ZDB-GENE-011108-2
- Name
- secreted frizzled-related protein 5
- Symbol
- sfrp5 Nomenclature History
- Previous Names
-
- sfrp1 (1)
- zgc:101849
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have Wnt-protein binding activity. Involved in several processes, including Wnt signaling pathway; animal organ development; and regulation of signal transduction. Predicted to localize to extracellular space. Is expressed in several structures, including anterior neural keel; anterior neural rod; gut; immature eye; and nervous system. Orthologous to human SFRP5 (secreted frizzled related protein 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101849 (29 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Stuckenholz et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001134 | Netrin domain |
| Domain | IPR018933 | Netrin module, non-TIMP type |
| Domain | IPR020067 | Frizzled domain |
| Domain | IPR041761 | SFRP5, cysteine-rich domain |
| Family | IPR015526 | Frizzled/secreted frizzled-related protein |
| Homologous_superfamily | IPR008993 | Tissue inhibitor of metalloproteinases-like, OB-fold |
| Homologous_superfamily | IPR036790 | Frizzled cysteine-rich domain superfamily |
Domain Details Per Protein
| Protein | Length | Frizzled cysteine-rich domain superfamily | Frizzled domain | Frizzled/secreted frizzled-related protein | Netrin domain | Netrin module, non-TIMP type | SFRP5, cysteine-rich domain | Tissue inhibitor of metalloproteinases-like, OB-fold |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6YNR8
|
310 |
Interactions and Pathways
No data available
Plasmids
No data available