Gene
dnase2
- ID
- ZDB-GENE-010724-16
- Name
- deoxyribonuclease II, lysosomal
- Symbol
- dnase2 Nomenclature History
- Previous Names
-
- fa56d08
- fa92d01
- wu:fa56d08
- wu:fa92d01
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable deoxyribonuclease II activity. Predicted to be involved in apoptotic DNA fragmentation. Predicted to act upstream of or within DNA metabolic process. Orthologous to human DNASE2 (deoxyribonuclease 2, lysosomal).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Matsui et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Autoinflammatory-pancytopenia syndrome | 619858 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR004947 | Deoxyribonuclease II |
Domain Details Per Protein
| Protein | Length | Deoxyribonuclease II |
|---|---|---|
|
UniProtKB:B0JZP5
|
367 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dnase2-201
(1)
|
Ensembl | 3,476 nt | ||
| mRNA |
dnase2-202
(1)
|
Ensembl | 2,781 nt |
Interactions and Pathways
No data available
Plasmids
No data available