Gene
ceacam1
- ID
- ZDB-GENE-010724-14
- Name
- CEA cell adhesion molecule 1
- Symbol
- ceacam1 Nomenclature History
- Previous Names
-
- hm:zeh0068
- zeh0068
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to be located in plasma membrane. Is expressed in several structures, including gill; heart; integument; muscle; and pleuroperitoneal region. Orthologous to several human genes including CEACAM5 (CEA cell adhesion molecule 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Kowalewski et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Immunoglobulin superfamily CEA-related | Immunoglobulin V-set domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PJ61 | InterPro | 667 | ||||||||
| UniProtKB:B0CLZ7 | InterPro | 1025 | ||||||||
| UniProtKB:A0AB32T280 | InterPro | 847 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ceacam1-201
(1)
|
Ensembl | 3,793 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(ceacam1:GFP-F) |
|
| 1 | Zebrafish Nomenclature Committee | |
| Tg(ceacam1:mCherryF) |
|
| 1 | (2) |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-250K15 | ZFIN Curated Data | |
| Contains | SNP | rs3728769 | ZFIN Curated Data | |
| Contains | SNP | rs3728770 | ZFIN Curated Data | |
| Contains | SNP | rs3728771 | ZFIN Curated Data | |
| Contains | SNP | rs3728772 | ZFIN Curated Data | |
| Encodes | EST | zeh0068 | Rajarao et al., 2001 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001113794 (1) | 3156 nt | ||
| Genomic | GenBank:BX005342 (1) | 257502 nt | ||
| Polypeptide | UniProtKB:B0CLZ7 (1) | 1025 aa |
| Species | Symbol | Chromosome | Accession # | Evidence |
|---|---|---|---|---|
| Human | CEACAM1 | 19 | Conserved genome location (synteny) (1) |
- Zebrafish Nomenclature Committee (2025) Nomenclature Data Curation (2025). Nomenclature Committee Submission.
- Li, Y., Liu, C., Bai, X., Li, M., Duan, C. (2023) FK506-binding protein 5 regulates cell quiescence-proliferation decision in zebrafish epithelium. FEBS letters. 597(14):1868-1879
- Kowalewski, J., Paris, T., Gonzalez, C., Lelièvre, E., Castaño Valencia, L., Boutrois, M., Augier, C., Lutfalla, G., Yatime, L. (2021) Characterization of a member of the CEACAM protein family as a novel marker of proton pump-rich ionocytes on the zebrafish epidermis. PLoS One. 16:e0254533
- Yoon, S., Mitra, S., Wyse, C., Alnabulsi, A., Zou, J., Weerdenburg, E.M., van der Sar, A.M., Wang, D., Secombes, C.J., Bird, S. (2015) First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio). PLoS One. 10:e0126378
- Mohseny, A.B., Xiao, W., Carvalho, R., Spaink, H.P., Hogendoorn, P.C., and Cleton-Jansen, AM. (2012) An osteosarcoma zebrafish model implicates Mmp-19 and Ets-1 as well as reduced host immune response in angiogenesis and migration. The Journal of pathology. 227(2):245-253
- Rajarao, S.J., Canfield, V.A., Mohideen, M.A., Yan, Y.-L., Postlethwait, J.H., Cheng, K.C., and Levenson, R. (2001) The repertoire of Na,K-ATPase alpha and beta subunit genes expressed in the zebrafish, Danio rerio. Genome research. 11(7):1211-1220
- Ton, C., Hwang, D.M., Dempsey, A.A., Tang, H.C., Yoon, J., Lim, M., Mably, J.D., Fishman, M.C., and Liew, C.C. (2000) Identification, characterization, and mapping of expressed sequence tags from an embryonic zebrafish heart cDNA library. Genome research. 10(12):1915-1927
- Geisler, R., Rauch, G.J., Baier, H., van Bebber, F., Brobeta, L., Dekens, M.P., Finger, K., Fricke, C., Gates, M.A., Geiger, H., Geiger-Rudolph, S., Gilmour, D., Glaser, S., Gnugge, L., Habeck, H., Hingst, K., Holley, S., Keenan, J., Kirn, A., Knaut, H., Lashkari, D., Maderspacher, F., Martyn, U., Neuhauss, S., Neumann, C., Nicolson, T., Pelegri, F., Ray, R., Rick, J.M., Roehl, H., Roeser, T., Schauerte, H.E., Schier, A.F., Schönberger, U., Schönthaler, H.-B., Schulte-Merker, S., Seydler, C., Talbot, W.S., Weiler, C., Nüsslein-Volhard, C., and Haffter, P. (1999) A radiation hybrid map of the zebrafish genome. Nature Genetics. 23(1):86-89
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