Gene
ucp1
- ID
- ZDB-GENE-010503-1
- Name
- uncoupling protein 1
- Symbol
- ucp1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable oxidative phosphorylation uncoupler activity. Acts upstream of or within cellular response to estrogen stimulus. Predicted to be located in membrane. Is expressed in several structures, including brain; heart; liver; median fin fold; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human UCP1 (uncoupling protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55824 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Mitochondrial carrier domain superfamily | Mitochondrial carrier protein | Mitochondrial Metabolite Transporter | Mitochondrial substrate/solute carrier |
|---|---|---|---|---|---|---|
| UniProtKB:Q7ZVP4 | InterPro | 309 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-ucp1 | monoclonal | IgG | Rabbit |
|
Cell Signaling Technology, Inc.
|
3 |
Plasmids
No data available