Gene
cldne
- ID
- ZDB-GENE-010328-5
- Name
- claudin e
- Symbol
- cldne Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable structural molecule activity. Acts upstream of or within epiboly involved in gastrulation with mouth forming second. Predicted to be located in cell junction and membrane. Predicted to be active in bicellular tight junction and plasma membrane. Is expressed in several structures, including EVL; blastomere; digestive system; ectoderm; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in ovarian cancer and pancreatic cancer. Orthologous to human CLDN4 (claudin 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 27 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb84 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Siddiqui et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Claudin | Claudin-2 | Claudin, conserved site | PMP-22/EMP/MP20/Claudin |
|---|---|---|---|---|---|
|
UniProtKB:Q90XR9
|
209 |
Interactions and Pathways
No data available
Plasmids
No data available