Gene
or40a1
- ID
- ZDB-GENE-010308-21
- Name
- odorant receptor, family 40, subfamily A, member 1
- Symbol
- or40a1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in olfactory epithelium; olfactory receptor cell; and olfactory rosette. Orthologous to several human genes including OR51D1 (olfactory receptor family 51 subfamily D member 1); OR51E1 (olfactory receptor family 51 subfamily E member 1); and OR51E2 (olfactory receptor family 51 subfamily E member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Olfactory receptor | Olfactory receptor 51/52/56-like |
|---|---|---|---|---|---|---|
| UniProtKB:Q9I8Y8 | InterPro | 379 | ||||
| UniProtKB:Q2PRD4 | InterPro | 331 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
or107-1-201
(1)
|
Ensembl | 1,399 nt | ||
| mRNA |
or107-1-202
(1)
|
Ensembl | 1,050 nt | ||
| mRNA |
or107-1-203
(1)
|
Ensembl | 1,376 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-133D24 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:194945 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:194966 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_131750 (1) | 1140 nt | ||
| Genomic | GenBank:AL845428 (1) | 157787 nt | ||
| Polypeptide | UniProtKB:Q9I8Y8 (1) | 379 aa |
No data available
- Zhu, H., Zhang, X., Xu, S., Wu, J., Hou, M., Zhao, H., Zhou, Q., Zhong, X. (2022) Gene duplication, conservation, and divergence of activating transcription factor 5 gene in zebrafish. Journal of experimental zoology. Part B, Molecular and developmental evolution. 338(5):301-313
- Behrens, M., Di Pizio, A., Redel, U., Meyerhof, W., Korsching, S.I. (2020) At the root of T2R gene evolution: Recognition profiles of coelacanth and zebrafish bitter receptors. Genome biology and evolution. 13(1)
- Olender, T., Jones, T.E.M., Bruford, E., Lancet, D. (2020) A unified nomenclature for vertebrate olfactory receptors. BMC Evolutionary Biology. 20:42
- Bayramli, X., Kocagöz, Y., Sakizli, U., Fuss, S.H. (2017) Patterned Arrangements of Olfactory Receptor Gene Expression in Zebrafish are Established by Radial Movement of Specified Olfactory Sensory Neurons. Scientific Reports. 7:5572
- Gao, S., Liu, S., Yao, J., Li, N., Yuan, Z., Zhou, T., Li, Q., Liu, Z. (2017) Genomic organization and evolution of olfactory receptors and trace amine-associated receptors in channel catfish, Ictalurus punctatus. Biochimica et biophysica acta. 1861(3):644-651
- Saraiva, L.R., Ahuja, G., Ivandic, I., Syed, A.S., Marioni, J.C., Korsching, S.I., Logan, D.W. (2015) Molecular and neuronal homology between the olfactory systems of zebrafish and mouse. Scientific Reports. 5:11487
- Ferreira, T., Wilson, S.R., Choi, Y.G., Risso, D., Dudoit, S., Speed, T.P., Ngai, J. (2014) Silencing of Odorant Receptor Genes by G Protein βγ Signaling Ensures the Expression of One Odorant Receptor per Olfactory Sensory Neuron. Neuron. 81(4):847-59
- Zhou, Y., Yan, X., Xu, S., Zhu, P., He, X., and Liu, J. (2011) Family structure and phylogenetic analysis of odorant receptor genes in the large yellow croaker (Larimichthys crocea). BMC Evolutionary Biology. 11(1):237
- Ng, Y.K., Wu, W., and Zhang, L. (2009) Positive correlation between gene coexpression and positional clustering in the zebrafish genome. BMC Genomics. 10:42
- Niimura, Y. (2009) On the Origin and Evolution of Vertebrate Olfactory Receptor Genes: Comparative Genome Analysis Among 23 Chordate Species. Genome biology and evolution. 1:34-44
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