ZFIN is now using GRCz12tu for Genomic Data
Gene
map2k6
- ID
- ZDB-GENE-010202-3
- Name
- mitogen-activated protein kinase kinase 6
- Symbol
- map2k6 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable MAP kinase kinase activity. Involved in positive regulation of p38MAPK cascade. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Pick's disease; cardiomyopathy (multiple); female reproductive organ cancer (multiple); and progressive supranuclear palsy. Orthologous to human MAP2K6 (mitogen-activated protein kinase kinase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55210 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q8K0 | InterPro | 416 | |||
| UniProtKB:Q9DGE0 | InterPro | 361 | |||
| UniProtKB:A0AB32TY69 | InterPro | 265 | |||
| UniProtKB:A0AC58GW72 | InterPro | 416 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map2k6-201
(1)
|
Ensembl | 3,308 nt | ||
| mRNA |
map2k6-202
(1)
|
Ensembl | 4,253 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers