Gene

eomesa

ID
ZDB-GENE-001228-1
Name
eomesodermin homolog a
Symbol
eomesa Nomenclature History
Previous Names
  • eom-a (1)
  • eom (1)
  • eomes1 (1)
  • eomes
  • tbr2 (1)
  • tbr2a (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Exhibits DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including determination of dorsal identity; epiboly; and gastrulation. Localizes to cytoplasm and nucleus. Is expressed in several structures, including blastoderm; blastodisc; brain; eye; and immune system. Orthologous to human EOMES (eomesodermin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
36 figures from 20 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Du et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eomesa Human Ortholog
No data available
Associated With eomesa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018186 Transcription factor, T-box, conserved site
Domain IPR032385 T-box transcription factor-associated
Family IPR001699 Transcription factor, T-box
Homologous_superfamily IPR008967 p53-like transcription factor, DNA-binding
Homologous_superfamily IPR036960 T-box superfamily
Domain Details Per Protein
Protein Length p53-like transcription factor, DNA-binding T-box superfamily T-box transcription factor-associated Transcription factor, T-box Transcription factor, T-box, conserved site
UniProtKB:Q9DDU3 661
UniProtKB:Q98TU2 661
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-eomesa polyclonal Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations