ZFIN is now using GRCz12tu for Genomic Data
Gene
eomesa
- ID
- ZDB-GENE-001228-1
- Name
- eomesodermin homolog a
- Symbol
- eomesa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within several processes, including determination of dorsal identity; epiboly; and gastrulation. Located in cytoplasm and nucleus. Is expressed in several structures, including blastoderm; blastodisc; brain; eye; and immune system. Orthologous to human EOMES (eomesodermin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 42 figures from 25 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu170 (12 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018186 | Transcription factor, T-box, conserved site |
| Domain | IPR032385 | T-box transcription factor-associated |
| Domain | IPR046360 | T-box transcription factor, DNA-binding domain |
| Family | IPR001699 | T-box transcription factor |
| Homologous_superfamily | IPR008967 | p53-like transcription factor, DNA-binding domain superfamily |
| Homologous_superfamily | IPR036960 | T-box superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | p53-like transcription factor, DNA-binding domain superfamily | T-box superfamily | T-box transcription factor | T-box transcription factor-associated | T-box transcription factor, DNA-binding domain | Transcription factor, T-box, conserved site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q98TU2 | InterPro | 661 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eomesa-201
(1)
|
Ensembl | 2,411 nt | ||
| mRNA |
eomesa-202
(1)
|
Ensembl | 2,507 nt | ||
| mRNA |
eomesa-203
(1)
|
Ensembl | 2,729 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-eomesa | polyclonal | Rabbit |
|
1 |
Plasmids
No data available
- Genome Browsers