Gene

nrf1

ID
ZDB-GENE-001221-1
Name
nuclear respiratory factor 1
Symbol
nrf1 Nomenclature History
Previous Names
  • nrf
  • nrl (1)
  • not really finished
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to cold; photoreceptor cell maintenance; and response to activity. Predicted to localize to nucleus. Is expressed in heart; nervous system; optic cup; and visceral fat. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human NRF1 (nuclear respiratory factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nrf1 Human Ortholog
No data available
Associated With nrf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR019525 Nuclear respiratory factor 1, NLS/DNA-binding, dimerisation domain
Domain IPR019526 Nuclear respiratory factor-1, activation binding domain
Family IPR039142 NRF1/Ewg family
Domain Details Per Protein
Protein Length NRF1/Ewg family Nuclear respiratory factor-1, activation binding domain Nuclear respiratory factor 1, NLS/DNA-binding, dimerisation domain
UniProtKB:Q90X44 514
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations