ZFIN ID: ZDB-GENE-000823-8
Gene Name: homeobox A11a
Gene Symbol: hoxa11a    Nomenclature History

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Previous Name: sb:eu415

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Predicted to be involved in multicellular organism development and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in several structures, including fin; fin bud; myoblast; retina; and tail bud. Human ortholog(s) of this gene implicated in radioulnar synostosis. Orthologous to human HOXA11 (homeobox A11).
Genome Resources: Alliance (1),  Gene:58061 (1),  Ensembl(GRCz11):ENSDARG00000104162 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la013394Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hoxa11a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Radioulnar synostosis with amegakaryocytic thrombocytopenia 1 605432
    DISEASE ASSOCIATED WITH hoxa11a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hoxa11a-201 (1)    Ensembl 997
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS
    Addgene:Hox A11a
    CONSTRUCTS WITH SEQUENCES FROM hoxa11a No data available
    MARKER RELATIONSHIPS
    hoxa11a Contained in: [BAC] DKEY-25E11 (1) (order this)
    hoxa11a Encodes: [EST] eu415 (1)
    [cDNA] MGC:194683 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131544 (1) 948 nt
    Genomic GenBank:CR382300 (1) 202006 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IBL5 (1) 315 aa
    Sequence Information (all 21)
    ORTHOLOGY for hoxa11a ( Chr: 19 )
    CITATIONS (51)