Gene

mxtx2

ID
ZDB-GENE-000710-6
Name
mix-type homeobox gene 2
Symbol
mxtx2 Nomenclature History
Previous Names
  • mtx2
  • zgc:136526
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Exhibits sequence-specific DNA binding activity. Involved in actin filament organization and gastrulation. Predicted to localize to nucleus. Is expressed in blastodisc; internal yolk syncytial layer; margin; marginal blastomere; and yolk syncytial layer. Orthologous to several human genes including DUX4L5 (double homeobox 4 like 5 (pseudogene)); DUX4L6 (double homeobox 4 like 6 (pseudogene)); and DUX4L7 (double homeobox 4 like 7 (pseudogene)).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mxtx2 Human Ortholog
No data available
Associated With mxtx2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001356 Homeodomain
Family IPR051306 Homeobox domain-containing regulator
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox domain-containing regulator Homeodomain
UniProtKB:Q1RM27 296
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mxtx2-201 (1) Ensembl 1,327 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations