ZFIN ID: ZDB-GENE-000607-70
Gene Name: hes-related family bHLH transcription factor with YRPW motif 1
Gene Symbol: hey1    Nomenclature History

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Previous Names: Herp1 (1), id:ibd1292 (1), zgc:110572

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in adenohypophysis development. Predicted to localize to nucleus. Is expressed in several structures, including germ ring; mesoderm; musculature system; nervous system; and pharyngeal arch. Orthologous to human HEY1 (hes related family bHLH transcription factor with YRPW motif 1).
Genome Resources: Alliance (1),  Gene:58008 (1),  Ensembl(GRCz11):ENSDARG00000070538 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ha7 Small Deletion Unknown Frameshift, Premature Stop TALEN
ha11 Small Deletion Unknown Frameshift, Premature Stop TALEN
sa17583 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hey1 N/A 1
    MO2-hey1 N/A 1
    MO3-hey1 N/A 1
    TALEN1-hey1 2
    DISEASE ASSOCIATED WITH hey1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hey1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process Notch signaling pathway (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hey1-201 (1)    Ensembl 3322
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hey1 No data available
    MARKER RELATIONSHIPS
    hey1 Contained in: [BAC] DKEYP-120H9 (1)
    hey1 Encodes: [EST] eu583 (1), ibd1292
    [cDNA] MGC:110572 (1), MGC:191286 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212561 (1) 3316 nt
    Genomic GenBank:BX927165 (1) 137449 nt
    Select Tool
    Polypeptide UniProtKB:B2GNV6 (1) 317 aa
    Sequence Information (all 21)
    ORTHOLOGY for hey1 ( Chr: 19 )
    CITATIONS (73)